Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.90 |
| ▸ | MEN1 | O00255 | 7/20 | 0.90 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.90 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.90 |
| ▸ | TUBB | P07437 | 7/20 | 0.90 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.90 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.90 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.90 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.90 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.90 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.90 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.90 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.90 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.90 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.90 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.90 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.90 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.90 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.90 |
| ▸ | LMNA | P02545 | 6/20 | 0.90 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vinblastine SCHEMBL4707820 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| SCHEMBL13529121 | 0.95 | TUBB4A (0.96) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL22022258 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL14445014 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL13279561 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL18613184 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL14077137 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL22450052 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL14601228 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB | |
| Vinblastine SCHEMBL13300979 | 0.95 | MAPT (1.00) | MAPTMEN1KMT2ATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210155592-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2021-05-27 | — | — | US | disclosed |
| US-10906875-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2021-02-02 | — | — | US | disclosed |
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2020-05-21 | — | — | US | disclosed |
| US-10343996-B2 | Quaternary heteroatom containing compounds | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2019-07-09 | — | — | US | disclosed |
| US-20170137382-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210155592-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | MAPT 2101/4885MEN1 758/4885KMT2A 114/4885 |
| US-10906875-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | MAPT 2101/4885MEN1 758/4885KMT2A 114/4885 |
| US-10343996-B2 | Quaternary heteroatom containing compounds | SDHA, NQO1, SDHB | MAPT 2101/4885MEN1 758/4885KMT2A 114/4885 |
| US-20200157049-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | MAPT 2101/4885MEN1 758/4885KMT2A 114/4885 |
| US-20170137382-A1 | QUATERNARY HETEROATOM CONTAINING COMPOUNDS | SDHA, NQO1, SDHB | MAPT 2101/4885MEN1 758/4885KMT2A 114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.