Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18664190 | 0.86 | HTT (0.38) | HTTALDH1A1KMT2A | |
| SCHEMBL26343600 | 0.84 | POLB (0.40) | ALDH1A1KMT2AMMP1MMP2MMP3 | |
| SCHEMBL18664188 | 0.82 | HTT (0.44) | HTTALDH1A1KMT2A | |
| SCHEMBL12955348 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL15795178 | 0.78 | KMT2A (0.37) | HTTALDH1A1KMT2AMMP1MMP2 | |
| SCHEMBL19026677 | 0.77 | HTT (0.42) | HTTALDH1A1KMT2AMMP1MMP2 | |
| SCHEMBL18664185 | 0.77 | ALDH1A1 (0.36) | HTTALDH1A1KMT2AMMP1MMP2 | |
| SCHEMBL18664186 | 0.77 | ALDH1A1 (0.36) | HTTALDH1A1KMT2AMMP1MMP2 | |
| SCHEMBL17617091 | 0.76 | — | — | |
| SCHEMBL19964705 | 0.71 | ALDH1A1 (0.35) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017046606-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2017-03-23 | — | — | WO | disclosed |