Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163820 | 0.77 | F10 (0.56) | F10KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13439739 | 0.74 | F10 (0.53) | F10KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL18640285 | 0.73 | F10 (0.47) | F10KDM4ESMN1; SMN2BCHEACHE | |
| SCHEMBL18639947 | 0.73 | F10 (0.54) | F10KDM4ESMN1; SMN2BCHEACHE | |
| SCHEMBL18640220 | 0.72 | F10 (0.47) | F10KDM4ESMN1; SMN2BCHEACHE | |
| SCHEMBL8935934 | 0.69 | MAP2K1 (0.53) | F10KDM4ESMN1; SMN2BCHEACHE | |
| SCHEMBL13512585 | 0.69 | KDM4E (0.61) | KDM4ESMN1; SMN2BCHEACHEL3MBTL1 | |
| SCHEMBL29210085 | 0.68 | KDM4E (0.61) | F10KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL6187603 | 0.67 | F10 (1.00) | F10 | |
| SCHEMBL803088 | 0.67 | KDM4E (0.59) | KDM4ESMN1; SMN2BCHEACHEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017045751-A1 | COMPOUNDS AS ASIC INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |