Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD51 | Q06609 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18666130 | 0.82 | SIRT1 (0.35) | RAD51IRAK4ABCB1GPR119SMN1; SMN2 | |
| SCHEMBL18665817 | 0.81 | KMT2A (0.37) | RAD51ABCB1MEN1KMT2AGPR119 | |
| SCHEMBL17048614 | 0.76 | KDM4E (0.45) | MEN1ALDH1A1KMT2AGPR119SMN1; SMN2 | |
| SCHEMBL17048612 | 0.76 | KDM4E (0.45) | MEN1ALDH1A1KMT2AGPR119SMN1; SMN2 | |
| SCHEMBL18665796 | 0.76 | KDM4E (0.45) | MEN1ALDH1A1KMT2AGPR119SMN1; SMN2 | |
| SCHEMBL122510 | 0.72 | RAD51 (0.53) | RAD51PIK3CDPIK3CAPIK3CBSMN1; SMN2 | |
| SCHEMBL232368 | 0.70 | RAD51 (0.54) | RAD51CYP11B1CYP11B2PIK3CDPIK3CA | |
| SCHEMBL121887 | 0.70 | RAD51 (0.54) | RAD51CYP11B1CYP11B2PIK3CDPIK3CA | |
| SCHEMBL230721 | 0.69 | RAD51 (0.43) | RAD51TBXA2RMEN1ALDH1A1KMT2A | |
| SCHEMBL230720 | 0.69 | RAD51 (0.43) | RAD51TBXA2RMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350173-B1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INT (DE) | 2020-02-12 | — | — | EP | disclosed |
| EP-3599234-A1 | STEREOSELECTIVE PROCESS | Boehringer Ingelheim International GmbH (DE) | 2020-01-29 | — | — | EP | disclosed |
| US-10189776-B2 | Stereoselective process | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| WO-2017046355-A1 | STEREOSELECTIVE PROCESS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10189776-B2 | Stereoselective process | CYP4A11, CYP4B1, CYP3A4 | RAD51 4127/4885CYP11B1 9/4885CYP11B2 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.