SCHEMBL18666148

SCHEMBL18666148

CC(CS(N)(=O)=O)C(F)(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.36
CA2 P00918 4/20 0.36
CA9 Q16790 3/20 0.36
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28832414 0.79
SCHEMBL18631344 0.75
SCHEMBL22529464 0.75 SLC22A6 (0.36)
SCHEMBL224667 0.69
SCHEMBL11688566 0.69 CA1 (0.43) CA1CA2CA9CA7
SCHEMBL24756672 0.67
Hydrochloric Acid SCHEMBL10876139 0.67
SCHEMBL7554263 0.67
SCHEMBL28364199 0.67
SCHEMBL18666140 0.67 CA2 (0.33) CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017048675-A1 SUBSTITUTED HETEROARYL COMPOUNDS AND METHODS OF USE SUNSHINE LAKE PHARMA CO., LTD. (CN) 2017-03-23 WO disclosed