Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 3/20 | 0.35 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13667812 | 1.00 | TNK2 (0.35) | TNK2HSPA5PDE2APDE4DTAAR1 | |
| SCHEMBL23822775 | 1.00 | TNK2 (0.35) | TNK2HSPA5PDE2APDE4DTAAR1 | |
| SCHEMBL23822961 | 0.88 | TNK2 (0.38) | TNK2HSPA5PDE2ATAAR1RIPK1 | |
| SCHEMBL22570014 | 0.87 | PDE4D (0.32) | TNK2HSPA5PDE4DBCHEACHE | |
| SCHEMBL23959858 | 0.86 | TNK2 (0.33) | TNK2HSPA5PDE2APDE4DTAAR1 | |
| SCHEMBL22355569 | 0.86 | TNK2 (0.33) | TNK2HSPA5PDE2APDE4DTAAR1 | |
| SCHEMBL12393373 | 0.82 | PDE2A (0.37) | TNK2HSPA5PDE2ABCHEGJB2 | |
| SCHEMBL27086454 | 0.82 | PDE2A (0.37) | TNK2HSPA5PDE2ABCHEGJB2 | |
| SCHEMBL31063739 | 0.82 | PDE2A (0.37) | TNK2HSPA5PDE2ABCHEGJB2 | |
| SCHEMBL12243141 | 0.82 | PDE2A (0.37) | TNK2HSPA5PDE2ABCHEGJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049060-A1 | METHODS FOR TREATING ARENAVIRIDAE AND CORONAVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |