Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 2/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22355569 | 1.00 | TNK2 (0.33) | TNK2HSPA5PDE2ATAAR1RIPK1 | |
| SCHEMBL18666953 | 0.86 | TNK2 (0.35) | TNK2HSPA5PDE2ATAAR1RIPK1 | |
| SCHEMBL13667812 | 0.86 | TNK2 (0.35) | TNK2HSPA5PDE2ATAAR1RIPK1 | |
| SCHEMBL23822775 | 0.86 | TNK2 (0.35) | TNK2HSPA5PDE2ATAAR1RIPK1 | |
| SCHEMBL18666852 | 0.82 | TNK2 (0.35) | TNK2HSPA5TAAR1CTSLCTSB | |
| SCHEMBL23822912 | 0.82 | TNK2 (0.35) | TNK2HSPA5TAAR1CTSLCTSB | |
| SCHEMBL12295037 | 0.82 | TNK2 (0.35) | TNK2HSPA5TAAR1CTSLCTSB | |
| SCHEMBL14817042 | 0.81 | HSPA5 (0.35) | TNK2HSPA5PDE2ABCHEHTR1A | |
| SCHEMBL20553048 | 0.81 | PDE2A (0.35) | HSPA5PDE2ABCHEACHEHTR1A | |
| SCHEMBL20477154 | 0.81 | PDE2A (0.35) | HSPA5PDE2ABCHEACHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021213288-A1 | ANTIVIRAL APPLICATION OF NUCLEOSIDE ANALOG OR COMBINATION FORMULATION CONTAINING NUCLEOSIDE ANALOG | 中国科学院上海药物研究所 (CN) | 2021-10-28 | — | — | WO | disclosed |