Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17085844 | 0.84 | L3MBTL1 (0.54) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL29355260 | 0.84 | TP53 (0.54) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL30186279 | 0.84 | L3MBTL1 (0.54) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL17085858 | 0.84 | TP53 (0.54) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL30271089 | 0.83 | L3MBTL1 (0.52) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL18667003 | 0.83 | L3MBTL1 (0.52) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL18667133 | 0.81 | L3MBTL1 (0.50) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL17085851 | 0.81 | CHEK1 (0.52) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL30186306 | 0.81 | CHEK1 (0.52) | L3MBTL1GAATSHRMAPK1TP53 | |
| SCHEMBL10669949 | 0.80 | L3MBTL1 (0.58) | L3MBTL1GAATSHRMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3782626-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2021-02-24 | — | — | EP | disclosed |
| WO-2017048950-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |