Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14639697 | 1.00 | PABPC1 (0.42) | PABPC1APOBEC3AAPOBEC3GTDP1CA1 | |
| SCHEMBL14639684 | 1.00 | PABPC1 (0.42) | PABPC1APOBEC3AAPOBEC3GTDP1CA1 | |
| SCHEMBL25740918 | 1.00 | PABPC1 (0.42) | PABPC1APOBEC3AAPOBEC3GTDP1CA1 | |
| SCHEMBL11430871 | 1.00 | PABPC1 (0.42) | PABPC1APOBEC3AAPOBEC3GTDP1CA1 | |
| SCHEMBL14403233 | 0.94 | — | — | |
| SCHEMBL27009541 | 0.94 | — | — | |
| SCHEMBL18720989 | 0.94 | — | — | |
| SCHEMBL26062934 | 0.94 | — | — | |
| SCHEMBL18721043 | 0.94 | — | — | |
| SCHEMBL33424 | 0.85 | TDP1 (0.50) | PABPC1APOBEC3AAPOBEC3GTDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049068-A1 | HETEROARYL COMPOUNDS AS IRAK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | WO | disclosed |