Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.78 |
| ▸ | HTR1A | P08908 | 6/20 | 0.78 |
| ▸ | DRD2 | P14416 | 6/20 | 0.78 |
| ▸ | HTR7 | P34969 | 6/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR1B | P28222 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668292 | 0.87 | HTR6 (1.00) | HTR6HTR1ADRD2HTR7CYP1A2 | |
| SCHEMBL18668321 | 0.87 | HTR6 (0.78) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL1249588 | 0.86 | HTR6 (0.78) | HTR6HTR1ADRD2HTR7CYP1A2 | |
| SCHEMBL18668316 | 0.78 | HTR6 (0.81) | HTR6HTR1ADRD2HTR7HTR2A | |
| SCHEMBL18668313 | 0.76 | HTR6 (0.79) | HTR6HTR1ADRD2HTR7CYP1A2 | |
| SCHEMBL1248660 | 0.76 | HTR6 (0.60) | HTR6HTR1ADRD2HTR7HTR2A | |
| SCHEMBL1248534 | 0.75 | HTR6 (0.82) | HTR6HTR1ADRD2HTR7HTR2C | |
| SCHEMBL1249738 | 0.75 | HTR6 (0.82) | HTR6HTR1ADRD2HTR7HTR2A | |
| SCHEMBL18668326 | 0.74 | HTR6 (1.00) | HTR6HTR1ADRD2HTR7HTR2A | |
| SCHEMBL18668335 | 0.74 | HTR6 (1.00) | HTR6HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017052394-A1 | IMIDAZOPYRIDINE COMPOUNDS AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | Uniwersytet Jagielloński (PL) | 2017-03-30 | — | — | WO | claimed |
| WO-2017052394-A1 | IMIDAZOPYRIDINE COMPOUNDS AND THEIR USE AS 5-HT6 RECEPTOR LIGANDS | Uniwersytet Jagielloński (PL) | 2017-03-30 | — | — | WO | disclosed |