Propionic Acid

Propionic Acid

SCHEMBL18668396

CCC(=O)O.Cn1ncnn1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.42
EGLN3 Q9H6Z9 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27672271 0.85 FFAR3 (0.33) FFAR3
Propionic Acid SCHEMBL28802772 0.78 FFAR3 (0.40) FFAR3L3MBTL1
Propionic Acid SCHEMBL27314793 0.66 FFAR3 (0.62) FFAR3EGLN3
Benzene SCHEMBL161390 0.65 FFAR3 (0.83) FFAR3L3MBTL1
Benzene SCHEMBL21273380 0.65 FFAR3 (0.83) FFAR3L3MBTL1
Benzene SCHEMBL29176309 0.65 FFAR3 (0.83) FFAR3L3MBTL1
Propionic Acid SCHEMBL1331605 0.65
Propionic Acid SCHEMBL11661434 0.65 FFAR3 (1.00) FFAR3
Propionic Acid SCHEMBL19409 0.65 FFAR3 (1.00) FFAR3
Propionic Acid SCHEMBL1462509 0.65 FFAR3 (1.00) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3353178-A1 NEW BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS H. Hoffnabb-La Roche Ag (CH) 2018-08-01 EP disclosed
WO-2017050791-A1 NEW BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS F. HOFFMANN-LA ROCHE AG (CH) 2017-03-30 WO disclosed