Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPY2R | P49146 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79668 | 1.00 | HDAC8 (0.67) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL2903467 | 1.00 | HDAC8 (0.67) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL29404405 | 1.00 | HDAC8 (0.67) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL29470165 | 1.00 | HDAC8 (0.67) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| Ethylene SCHEMBL28650882 | 0.96 | HDAC8 (0.63) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL28812132 | 0.90 | HDAC8 (0.55) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL11138672 | 0.88 | PARP1 (0.69) | HDAC8HDAC6MAPTCA1CA2 | |
| SCHEMBL8746630 | 0.88 | PARP1 (0.69) | HDAC8HDAC6MAPTCA1CA2 | |
| SCHEMBL1233027 | 0.87 | HDAC8 (0.57) | HDAC8HDAC6MAPTALDH1A1CYP1A1 | |
| SCHEMBL3979958 | 0.87 | HDAC8 (0.57) | HDAC8HDAC6MAPTALDH1A1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429768-B1 | NOVEL MEDICAMENTS FOR INHALATION | BOEHRINGER INGELHEIM PHARMA (DE) | 2016-11-16 | — | — | EP | claimed |
| US-20050256149-A1 | Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-11-17 | — | — | US | claimed |
| US-6919325-B2 | Respiratory system disorders; synergistic mixtures | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2005-07-19 | — | — | US | claimed |
| EP-1429768-A1 | NOVEL MEDICAMENTS FOR INHALATION | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-06-23 | — | — | EP | claimed |
| US-20030130300-A1 | Respiratory system disorders; synergistic mixtures | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-07-10 | — | — | US | claimed |
| WO-2003024452-A1 | NOVEL MEDICAMENTS FOR INHALATION | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-03-27 | — | — | WO | claimed |
| JP-9067332-A | — | — | None | — | — | JP | disclosed |
| US-20250313539-A1 | Alpha, Beta-UNSATURATED AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | KUNMING INSTITUTE OF ZOOLOGY, CHINESE ACADEMY OF SCIENCES (CN) | 2025-10-09 | — | — | US | disclosed |
| CN-114591255-B | Pleuromutilin derivative containing 1,2, 4-triazole acrylamide side chain and preparation method and application thereof | 西安康远晟生物医药科技有限公司 | 2024-04-16 | — | — | CN | disclosed |
| CN-117402123-A | Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-01-16 | — | — | CN | disclosed |
| CN-117264935-A | Phenylalanine ammonia lyase mutant and application thereof | 中国科学院成都生物研究所 | 2023-12-22 | — | — | CN | disclosed |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-10-17 | — | — | US | disclosed |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-10-17 | — | — | US | disclosed |
| US-4153617-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1979-05-08 | — | — | US | disclosed |
| US-4152159-A | ACRYLIC ESTER POLYMERS | EASTMAN KODAK COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4148909-A | Chromans to treat depression and reduce appetite | BEECHAM GROUP LIMITED (GB) | 1979-04-10 | — | — | US | disclosed |
| US-4146539-A | MOOD MODIFYERS, ANTIDEPRESSANTS | BEECHAM GROUP LIMITED (GB) | 1979-03-27 | — | — | US | disclosed |
| US-4133883-A | Polycyclic chromenes useful as antidepressants and anorexics | BEECHAM GROUP LIMITED (GB) | 1979-01-09 | — | — | US | disclosed |
| US-4080335-A | Anorexic chromans | BEECHAM GROUP LIMITED (GB) | 1978-03-21 | — | — | US | disclosed |
| US-4074046-A | REACTING NITROGENEOUS COMPOUND WITH CARBON MONOXIDE | AMERICAN CYANAMID COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256149-A1 | Pharmaceutical compositions containing tiotropium salts and low-solubility salmeterol salts | ADRB3, ADRB1, HSD3B1 | HDAC8 3668/4885HDAC6 1028/4885MAPT 1271/4885 |
| US-11793064-B2 | Organic metal complex, and organic light emitting device and display apparatus using the same | L1CAM, AP2M1, MRPL9 | HDAC8 4803/4885HDAC6 4673/4885MAPT 2518/4885 |
| US-20030130300-A1 | Respiratory system disorders; synergistic mixtures | ADRB3, ADRB1, CHRM3 | HDAC8 4021/4885HDAC6 1492/4885MAPT 2558/4885 |
| US-20250313539-A1 | Alpha, Beta-UNSATURATED AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | DEGS1, ACAD11, HADHA | HDAC8 941/4885HDAC6 1485/4885MAPT 245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.