SCHEMBL18669014

SCHEMBL18669014

O=C(NCCN1CCCCC1)c1ccc2c(c1)C(=O)N(Cc1c(Cl)cccc1Cl)C2=O

nearest known ligand 0.80

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CACNA1G O43497 20/20 0.80

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5008512 0.88 CACNA1G (1.00) CACNA1G
Hydrochloric Acid SCHEMBL5010948 0.87 CACNA1G (0.98) CACNA1G
Hydrochloric Acid SCHEMBL5010969 0.86 CACNA1G (1.00) CACNA1G
Hydrochloric Acid SCHEMBL5009987 0.85 CACNA1G (1.00) CACNA1G
Hydrochloric Acid SCHEMBL5010958 0.85 CACNA1G (1.00) CACNA1G
Hydrochloric Acid SCHEMBL5008571 0.85 CACNA1G (0.98) CACNA1G
Hydrochloric Acid SCHEMBL5013739 0.84 CACNA1G (0.98) CACNA1G
Hydrochloric Acid SCHEMBL5010030 0.84 CACNA1G (0.98) CACNA1G
Hydrochloric Acid SCHEMBL5010566 0.83 CACNA1G (1.00) CACNA1G
Hydrochloric Acid SCHEMBL5010963 0.82 CACNA1G (1.00) CACNA1G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017049409-A1 COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) 2017-03-30 WO disclosed
WO-2017049409-A1 COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) 2017-03-30 WO disclosed