SCHEMBL186697

SCHEMBL186697

CCCCc1ccccc1[O]

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.47
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
NR1H2 P55055 1/20 0.42
NR1H3 Q13133 1/20 0.42
CYSLTR2 Q9NS75 7/20 0.41
CYSLTR1 Q9Y271 7/20 0.41
TLR8 Q9NR97 1/20 0.41
CTRC Q99895 1/20 0.40
BID P55957 2/20 0.40
BCL2L1 Q07817 2/20 0.40
MCL1 Q07820 2/20 0.40
BAK1 Q16611 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL376413 0.93 LIPG (0.55) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL659946 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL660368 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL395906 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL11226283 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL2678792 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL395989 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL2679239 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL4325574 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1
SCHEMBL396018 0.91 LIPG (0.58) LIPGNR1H2NR1H3CYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2484 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410239-A Heteroatom-containing metallocene compound and preparation method and application thereof 惠生(中国)投资有限公司 2023-07-11 CN claimed
CN-110818545-B Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2022-12-09 CN claimed
CN-110922286-B Asymmetric aryl substituted fulvene compound and preparation method and application thereof 上海化工研究院有限公司 2022-08-16 CN claimed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN claimed
WO-2021122709-A1 TEXTILE COATED WITH MALODOR REDUCING POLYMERS BASF SE (DE) 2021-06-24 WO claimed
WO-2021122692-A1 TEXTILE COATED WITH MALODOR REDUCING POLYMERS BASF SE (DE) 2021-06-24 WO claimed
WO-2021122698-A1 TEXTILE COATED WITH MALODOR REDUCING POLYMERS BASF SE (DE) 2021-06-24 WO claimed
US-10745372-B2 Compound, resin, material for forming underlayer film for lithography, underlayer film for lithography, pattern forming method, and purification method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-08-18 US claimed
CN-110922286-A Asymmetric aryl substituted fulvene compound and preparation method and application thereof 上海化工研究院有限公司 2020-03-27 CN claimed
CN-110818545-A Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2020-02-21 CN claimed
WO-2000063260-A1 METHOD FOR THE PRODUCTION OF A CONTROLLED RHEOLOGICAL POLYPROPYLENE RESIN ATOFINA (FR) 2000-10-26 WO claimed
WO-2000018723-A1 SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
WO-1998056878-A1 ADDITIVES ENABLING BLENDING OF POLAR AND NON-POLAR FUEL COMPONENTS CRAIG DONALD MURRAY (CA) 1998-12-17 WO claimed
CN-1139435-A New ginkgolide derivatives and process for preparing them SUNKYONG IND LTD (KR) 1997-01-01 CN claimed
EP-0244126-B1 TETRABROMO BISPHENOL BASED POLYESTERCARBONATE MEMBRANES AND METHOD OF USING THE DOW CHEMICAL COMPANY (US) 1992-05-13 EP claimed
EP-0335214-A2 Polycarbonate IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1989-10-04 EP claimed
US-4859569-A Optical recording medium MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-08-22 US claimed
US-4840646-A SEPARATION OF OXYGEN FROM NITROGEN IN GAS MIXTURES THE DOW CHEMICAL COMPANY (US) 1989-06-20 US claimed
CN-87103123-A The polycarbonate membrane of tetrabromobisphenol type and using method 1987-12-16 CN claimed
EP-0244126-A2 Tetrabromo bisphenol based polyestercarbonate membranes and method of using THE DOW CHEMICAL COMPANY (US) 1987-11-04 EP claimed