Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 16/20 | 0.63 |
| ▸ | P2RY4 | P51582 | 11/20 | 0.63 |
| ▸ | POLA1 | P09884 | 1/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672084 | 0.90 | P2RY2 (0.60) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL23171577 | 0.85 | POLA1 (0.59) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL18672128 | 0.84 | POLA1 (0.62) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL18672079 | 0.83 | P2RY2 (0.56) | P2RY2P2RY4POLA1P2RY6 | |
| SCHEMBL9465485 | 0.83 | P2RY2 (0.70) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL18672129 | 0.82 | POLA1 (0.63) | P2RY2P2RY4POLA1P2RY6 | |
| SCHEMBL5034568 | 0.81 | P2RY2 (0.66) | P2RY2P2RY4POLA1P2RY6 | |
| SCHEMBL19558286 | 0.77 | P2RY2 (1.00) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL14853792 | 0.77 | P2RY2 (1.00) | P2RY2P2RY4POLA1P2RY6P2RY14 | |
| SCHEMBL21006621 | 0.77 | P2RY2 (1.00) | P2RY2P2RY4POLA1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603863-B2 | Substituted nucleosides, nucleotides and analogs thereof | ALIOS BIOPHARMA, INC. (US) | 2017-03-28 | — | — | US | disclosed |