Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13224082 | 1.00 | RARB (0.37) | RARBSLC7A5DPP4BLMLMNA | |
| SCHEMBL22390222 | 0.98 | RARB (0.36) | RARBSLC7A5DPP4BLMLMNA | |
| SCHEMBL20919191 | 0.98 | RARB (0.36) | RARBSLC7A5DPP4BLMLMNA | |
| SCHEMBL19387347 | 0.94 | SLC7A5 (0.38) | RARBSLC7A5DPP4BLMDPP8 | |
| SCHEMBL19387340 | 0.94 | SLC7A5 (0.38) | RARBSLC7A5DPP4BLMDPP8 | |
| SCHEMBL19750463 | 0.94 | SLC7A5 (0.38) | RARBSLC7A5DPP4BLMDPP8 | |
| SCHEMBL6368605 | 0.90 | SLC7A5 (0.44) | SLC7A5DPP4DPP8DPP9DPP7 | |
| SCHEMBL30058717 | 0.89 | TP53 (0.38) | RARBDPP4DPP8DPP9DPP7 | |
| SCHEMBL14095430 | 0.88 | SLC7A5 (0.42) | SLC7A5DPP4TSHRPSMB5 | |
| SCHEMBL26231092 | 0.88 | SLC7A5 (0.42) | SLC7A5DPP4TSHRPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603895-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-03-28 | — | — | US | disclosed |