Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 5/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22390222 | 0.91 | RARB (0.36) | TSHRRARBNAAANOD1DPP4 | |
| SCHEMBL20919191 | 0.91 | RARB (0.36) | TSHRRARBNAAANOD1DPP4 | |
| SCHEMBL13224082 | 0.89 | RARB (0.37) | TSHRRARBDPP4DPP8DPP9 | |
| SCHEMBL18672811 | 0.89 | RARB (0.37) | TSHRRARBDPP4DPP8DPP9 | |
| SCHEMBL30059110 | 0.88 | TP53 (0.36) | TP53NOD1DPP4DPP8DPP9 | |
| SCHEMBL31584745 | 0.88 | TSHR (0.45) | TP53TSHRNAAASTSEPHX1 | |
| SCHEMBL30057774 | 0.88 | TSHR (0.45) | TP53TSHRNAAASTSEPHX1 | |
| SCHEMBL30058881 | 0.88 | TSHR (0.45) | TP53TSHRNAAASTSEPHX1 | |
| SCHEMBL28666412 | 0.88 | TSHR (0.45) | TP53TSHRNAAASTSEPHX1 | |
| SCHEMBL30060725 | 0.88 | TSHR (0.45) | TP53TSHRNAAASTSEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2025-03-18 | — | — | US | claimed |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORPORATION | 2023-03-23 | — | — | US | claimed |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2023-01-03 | — | — | US | claimed |
| US-20250186322-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORP (US) | 2025-06-12 | — | — | US | disclosed |
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2025-03-18 | — | — | US | disclosed |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | INOLEX INVESTMENT CORPORATION | 2023-03-23 | — | — | US | disclosed |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | INOLEX INVESTMENT CORPORATION (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12251457-B2 | Self-neutralizing amino acid based cationic compositions | SLC6A15, SLC1A5, SLC6A19 | TP53 2069/4885TSHR 3595/4885RARB 3917/4885 |
| US-20250186322-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | SLC43A1, SLC1A5, SLC7A1 | TP53 1869/4885TSHR 2332/4885RARB 4165/4885 |
| US-20230092150-A1 | Self-Neutralizing Amino Acid Based Cationic Compositions | SLC6A15, SLC1A5, SLC6A19 | TP53 2069/4885TSHR 3595/4885RARB 3917/4885 |
| US-11540991-B2 | Self-neutralizing amino acid based cationic compositions | SLC6A15, SLC1A5, SLC6A19 | TP53 2069/4885TSHR 3595/4885RARB 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.