Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL940260 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL18649880 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915328 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20936481 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20936607 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL10950345 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915528 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915262 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915274 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL6050372 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9603895-B2 | Cyclosporin analogues for preventing or treating hepatitis C infection | ENANTA PHARMACEUTICALS, INC. (US) | 2017-03-28 | — | — | US | disclosed |