Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.39 |
| ▸ | KDR | P35968 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18672829 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL18649880 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915328 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20936481 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20936607 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL10950345 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915528 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915262 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL20915274 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R | |
| SCHEMBL6050372 | 1.00 | MEN1 (0.62) | MEN1ALDH1A1KMT2ATBXAS1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109135060-A | A kind of foamed heat-insulating material and preparation method thereof based on polypropylene matrix | 丹阳博亚新材料技术服务有限公司 | 2019-01-04 | — | — | CN | claimed |
| CN-109135060-B | Foamed heat-insulating material mainly based on polypropylene matrix and preparation method thereof | 丹阳博亚新材料技术服务有限公司 | 2023-03-28 | — | — | CN | disclosed |
| US-11198691-B2 | N-((het)arylmethyl)-heteroaryl-carboxamides compounds as kallikrein inhibitors | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2021-12-14 | — | — | US | disclosed |
| US-10966967-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-04-06 | — | — | US | disclosed |
| US-20200281905-A1 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-09-10 | — | — | US | disclosed |
| US-20200199116-A1 | N-((HET)Arylmethyl)-Heteroaryl-Carboxamides Compounds As Kallikrein Inhibitors | DRI UK LP (KY) | 2020-06-25 | — | — | US | disclosed |
| CN-109135060-A | A kind of foamed heat-insulating material and preparation method thereof based on polypropylene matrix | 丹阳博亚新材料技术服务有限公司 | 2019-01-04 | — | — | CN | disclosed |
| US-9809545-B2 | Factor XIa inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-11-07 | — | — | US | disclosed |
| US-20110015403-A1 | PROCESS FOR PREPARING IODINATED AZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2011-01-20 | — | — | US | disclosed |
| US-20090306397-A1 | Method for the production of substituted azoles | LANXESS DEUTSCHLAND GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
| EP-1979333-A1 | PROCESS FOR PREPARING IODINATED AZOLES | Lanxess Deutschland GmbH (DE) | 2008-10-15 | — | — | EP | disclosed |
| EP-1891025-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | Lanxess Deutschland GmbH (DE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2007085349-A1 | PROCESS FOR PREPARING IODINATED AZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2006131228-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED AZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199116-A1 | N-((HET)Arylmethyl)-Heteroaryl-Carboxamides Compounds As Kallikrein Inhibitors | KLKB1, BDKRB1, BDKRB2 | MEN1 826/4885ALDH1A1 3143/4885KMT2A 430/4885 |
| US-20090306397-A1 | Method for the production of substituted azoles | CYP11B1, CYP11B2, CYP4F11 | MEN1 199/4885ALDH1A1 389/4885KMT2A 1480/4885 |
| US-11198691-B2 | N-((het)arylmethyl)-heteroaryl-carboxamides compounds as kallikrein inhibitors | KLKB1, BDKRB1, BDKRB2 | MEN1 826/4885ALDH1A1 3143/4885KMT2A 430/4885 |
| US-10966967-B2 | Aryl dihydropyridinones and piperidinone MGAT2 inhibitors | DGAT2, MGAT2, MGAT1 | MEN1 2323/4885ALDH1A1 284/4885KMT2A 155/4885 |
| US-20200281905-A1 | ARYL DIHYDROPYRIDINONES AND PIPERIDINONE MGAT2 INHIBITORS | DGAT2, MGAT2, MGAT1 | MEN1 2323/4885ALDH1A1 284/4885KMT2A 155/4885 |
| US-20110015403-A1 | PROCESS FOR PREPARING IODINATED AZOLES | AZI2, TPO, INSR | MEN1 61/4885ALDH1A1 2523/4885KMT2A 2140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.