SCHEMBL186730

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL186398	0.91	HDAC1 (0.35)	TRPA1NAMPTHDAC3HDAC1HDAC2
	SCHEMBL186050	0.91	CNR1 (0.36)	TRPA1NAMPTHDAC3HDAC1HDAC2
	SCHEMBL186387	0.91	KCNQ3 (0.42)	HDAC3HDAC1HDAC2HDAC6BDKRB1
	SCHEMBL185570	0.90	ALDH1A1 (0.36)	TRPA1HDAC3HDAC1HDAC2HDAC6
	SCHEMBL2807486	0.90	HDAC3 (0.41)	TRPA1HDAC3HDAC1HDAC2HDAC6
	SCHEMBL2811921	0.89	HDAC3 (0.38)	TRPA1HDAC3HDAC1HDAC2HDAC6
	SCHEMBL185915	0.89	ABL1 (0.38)	HDAC3HDAC1HDAC2HDAC6BDKRB1
	SCHEMBL186506	0.89	AR (0.38)	TRPA1HDAC3HDAC1HDAC2HDAC6
	SCHEMBL2805859	0.88	BDKRB1 (0.41)	TRPA1HDAC3HDAC1HDAC2HDAC6
	SCHEMBL186319	0.88	BDKRB1 (0.49)	TRPA1NAMPTHDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.