Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.53 |
| ▸ | PKD1 | P98161 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17922332 | 0.75 | MAP3K14 (0.71) | MAP3K14PKD1 | |
| SCHEMBL16547245 | 0.69 | MAP3K14 (0.85) | MAP3K14PKD1 | |
| SCHEMBL16532276 | 0.69 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL16517349 | 0.69 | MAP3K14 (1.00) | MAP3K14PKD1 | |
| SCHEMBL16532371 | 0.68 | MAP3K14 (0.82) | MAP3K14PKD1 | |
| SCHEMBL16516989 | 0.68 | MAP3K14 (0.86) | MAP3K14PKD1 | |
| SCHEMBL18673445 | 0.66 | MAP3K14 (0.75) | MAP3K14PKD1 | |
| SCHEMBL31691059 | 0.65 | METAP2 (0.53) | — | |
| SCHEMBL26644107 | 0.65 | METAP2 (0.53) | — | |
| SCHEMBL26644429 | 0.65 | METAP2 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9605005-B2 | Alkynyl alcohols and methods of use | GENENTECH, INC. (US) | 2017-03-28 | — | — | US | disclosed |