Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18674646 | 0.93 | ALDH1A1 (0.39) | ALDH1A1NOS1SMN1; SMN2SLC29A1MAPK1 | |
| SCHEMBL22334912 | 0.91 | SMN1; SMN2 (0.40) | CRHR1ALDH1A1NOS1SMN1; SMN2MAPK1 | |
| SCHEMBL18674687 | 0.90 | SLC29A1 (0.37) | ALDH1A1NOS1SMN1; SMN2SLC29A1MAPK1 | |
| SCHEMBL18674644 | 0.88 | SLC29A1 (0.42) | ALDH1A1NOS1SMN1; SMN2SLC29A1MAPK1 | |
| SCHEMBL18674625 | 0.83 | MEN1 (0.39) | CRHR1ALDH1A1SLC29A1MAPK1LMNA | |
| SCHEMBL18678344 | 0.79 | KDM4E (0.39) | ALDH1A1LMNAKDM4EMEN1KMT2A | |
| SCHEMBL3506347 | 0.79 | MAPK1 (0.42) | ALDH1A1NOS1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL18674632 | 0.77 | MEN1 (0.42) | ALDH1A1SLC29A1MAPK1LMNAKDM4E | |
| SCHEMBL17014748 | 0.76 | AR (0.39) | CRHR1ALDH1A1MEN1KMT2A | |
| SCHEMBL17014845 | 0.75 | MEN1 (0.39) | ALDH1A1SMN1; SMN2LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3142638-B1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | OREAL (FR) | 2020-08-12 | — | — | EP | claimed |
| US-9993409-B2 | Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler | L'OREAL (FR) | 2018-06-12 | — | — | US | disclosed |
| US-9993409-B2 | Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler | L'OREAL (FR) | 2018-06-12 | — | — | US | disclosed |
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | L'OREAL (FR) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170087075-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER | KRT18, F12, CBR3 | CRHR1 1657/4885ALDH1A1 515/4885NOS1 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.