Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.70 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280516 | 0.81 | RIPK1 (0.67) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL13851912 | 0.80 | TAAR1 (0.52) | RIPK1TAAR1TRPA1AOC3HRH1 | |
| SCHEMBL4601134 | 0.80 | TAAR1 (0.52) | RIPK1TAAR1TRPA1AOC3HRH1 | |
| SCHEMBL21216505 | 0.80 | TAAR1 (0.52) | RIPK1TAAR1TRPA1AOC3HRH1 | |
| SCHEMBL21227003 | 0.80 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL11137800 | 0.79 | HRH1 (0.52) | RIPK1TAAR1HRH1 | |
| SCHEMBL435735 | 0.79 | RIPK1 (0.46) | RIPK1AOC3 | |
| SCHEMBL5213988 | 0.79 | RIPK1 (0.64) | RIPK1TAAR1TRPA1AOC3 | |
| Lithium SCHEMBL30777534 | 0.79 | RIPK1 (0.64) | RIPK1TAAR1TRPA1AOC3 | |
| SCHEMBL23336071 | 0.77 | TAAR1 (0.67) | RIPK1TAAR1TRPA1AOC3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017051354-A1 | MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-03-30 | — | — | WO | disclosed |