Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 14/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123093 | 0.90 | CAPN1 (0.61) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14122814 | 0.88 | CAPN1 (0.66) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL15579527 | 0.88 | CAPN1 (0.54) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14123169 | 0.85 | CAPN1 (0.56) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14123116 | 0.85 | CAPN1 (0.56) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14122945 | 0.85 | CAPN1 (0.56) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL12638750 | 0.83 | CTSL (0.73) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14123115 | 0.83 | CAPN1 (0.54) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14123226 | 0.82 | CAPN1 (0.54) | CAPN1CTSBCTSLCAPN9MAPK1 | |
| SCHEMBL14122916 | 0.81 | CAPN1 (0.53) | CAPN1CTSBCTSLCAPN9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017053864-A1 | CYSTEINE PROTEASE INHIBITORS | INTRACELLULAR TECHNOLOGIES, LLC (US) | 2017-03-30 | — | — | WO | disclosed |