Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18679281 | 1.00 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18684098 | 0.98 | MEN1 (0.34) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679283 | 0.98 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679658 | 0.97 | AKR1C4 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679653 | 0.97 | AKR1C4 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679351 | 0.97 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679348 | 0.96 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679284 | 0.96 | MEN1 (0.36) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679209 | 0.96 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDMAPT | |
| SCHEMBL18679208 | 0.96 | MEN1 (0.35) | MEN1KMT2AALDH1A1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170092872-A1 | ORGANIC LIGHT-EMITTING DEVICE | OR10J3, L1CAM, EML4 | MEN1 1002/4885KMT2A 2240/4885ALDH1A1 50/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.