Sugi Predict

Sugi Predict / Compounds / SCHEMBL18680465

SCHEMBL18680465

SCHEMBL18680465

c1ccc2c(c1)Cc1ccccc1N2c1ccc(-c2nc3cc4oc(-c5ccc(N6c7ccccc7Oc7ccccc76)cc5)nc4cc3s2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NPC1 O15118 8/20 0.38
▸ RAB9A P51151 8/20 0.38
▸ SMN1; SMN2 Q16637 7/20 0.38
▸ PKM P14618 2/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.38
▸ KDM4E B2RXH2 5/20 0.34
▸ HPGD P15428 5/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ TP53 P04637 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ MAPT P10636 2/20 0.34
▸ NFKB1 P19838 2/20 0.34
▸ NFKB2 Q00653 2/20 0.34
▸ RELA Q04206 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ APP P05067 4/20 0.33
▸ GFER P55789 2/20 0.33
▸ GAA P10253 1/20 0.33
▸ STAT1 P42224 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283223 0.93 NPC1 (0.40) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL17283363 0.91 SMN1; SMN2 (0.40) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL18680458 0.91 NPC1 (0.44) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL18680429 0.90 NPC1 (0.42) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL18680467 0.89 NPC1 (0.38) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL17283229 0.84 SMN1; SMN2 (0.42) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL17283207 0.84 NPC1 (0.47) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL17283366 0.83 SMN1; SMN2 (0.41) NPC1RAB9ASMN1; SMN2PKMKMT2A
SCHEMBL17283238 0.82 NPC1 (0.48) NPC1RAB9ASMN1; SMN2KMT2AKDM4E
SCHEMBL17283271 0.81 NPC1 (0.45) NPC1RAB9ASMN1; SMN2PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 — — US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 — — US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 NPC1 2870/4885RAB9A 1728/4885SMN1; SMN2 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.