SCHEMBL17283229

SCHEMBL17283229

c1ccc(N2c3ccccc3N(c3ccc(-c4nc5cc6sc(-c7ccc(N8c9ccccc9N(c9ccccc9)c9ccccc98)cc7)nc6cc5o4)cc3)c3ccccc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 11/20 0.42
NPC1 O15118 9/20 0.42
RAB9A P51151 8/20 0.42
PKM P14618 3/20 0.42
KMT2A Q03164 3/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 8/20 0.39
HPGD P15428 6/20 0.39
ALDH1A1 P00352 5/20 0.39
MAPT P10636 4/20 0.39
LMNA P02545 3/20 0.39
NFKB1 P19838 3/20 0.39
NFKB2 Q00653 3/20 0.39
RELA Q04206 3/20 0.39
TP53 P04637 3/20 0.39
GAA P10253 2/20 0.39
STAT1 P42224 1/20 0.39
GFER P55789 1/20 0.39
CASP3 P42574 2/20 0.39
SENP7 Q9BQF6 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17283366 0.99 SMN1; SMN2 (0.41) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283365 0.90 SMN1; SMN2 (0.38) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283363 0.90 SMN1; SMN2 (0.40) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283223 0.90 NPC1 (0.40) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283220 0.90 NPC1 (0.40) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283236 0.88 NPC1 (0.51) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283211 0.88 RAB9A (0.51) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283367 0.88 SMN1; SMN2 (0.40) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL18680466 0.87 NPC1 (0.38) SMN1; SMN2NPC1RAB9APKMKMT2A
SCHEMBL17283272 0.86 KDM4E (0.50) SMN1; SMN2NPC1RAB9APKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2023-11-23 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency UDC IRELAND LIMITED (IE) 2023-07-18 US disclosed
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency UDC IRELAND LTD (IE) 2020-08-13 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency BASF SE (DE) 2017-03-30 US disclosed
WO-2015176981-A1 FLUORESCENT ORGANIC LIGHT EMITTING ELEMENTS HAVING HIGH EFFICIENCY BASF SE (DE) 2015-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230380277-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 SMN1; SMN2 2504/4885NPC1 2870/4885RAB9A 1728/4885
US-11706978-B2 Fluorescent organic light emitting elements having high efficiency TEAD1, TEAD2, TEAD4 SMN1; SMN2 2504/4885NPC1 2870/4885RAB9A 1728/4885
US-20170092874-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 SMN1; SMN2 2504/4885NPC1 2870/4885RAB9A 1728/4885
US-20200259100-A1 Fluorescent Organic Light Emitting Elements Having High Efficiency TEAD1, TEAD2, TEAD4 SMN1; SMN2 2504/4885NPC1 2870/4885RAB9A 1728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.