Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.73 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218122 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL30824648 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL196056 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL1065817 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL181505 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| Cyclohexyl Palmitate SCHEMBL3653509 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL3660765 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL11417497 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL8736624 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 | |
| SCHEMBL27924851 | 0.85 | NAAA (1.00) | NAAAHTTEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | RQX PHARMACEUTICALS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| US-10351595-B2 | — | — | 2019-07-16 | — | — | US | disclosed |
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS, INC. (US) | 2017-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351595-B2 | — | MRPL21, PRSS1, PEPD | NAAA 480/4885FAAH 2818/4885DNM1 1853/4885 |
| US-10392422-B2 | Macrocyclic broad spectrum antibiotics | MRPL21, PEPD, CTSC | NAAA 742/4885FAAH 3193/4885DNM1 1403/4885 |
| US-20170088582-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | MRPL21, PEPD, CTSC | NAAA 742/4885FAAH 3193/4885DNM1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.