SCHEMBL186818

SCHEMBL186818

CCOC(=O)C(C)(C)CCCCCBr

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.71
CYP4A11 Q02928 3/20 0.71
HTT P42858 1/20 0.46
PKM P14618 3/20 0.43
THRB P10828 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
ATM Q13315 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 2/20 0.38
TRPA1 O75762 1/20 0.38
ELANE P08246 2/20 0.35
ACLY P53396 1/20 0.35
ACACB O00763 1/20 0.34
ACACA Q13085 1/20 0.34
MMP8 P22894 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL186284 1.00 CYP4F2 (0.71) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL2142612 1.00 CYP4F2 (0.71) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL9871166 1.00 CYP4F2 (0.71) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL186838 0.98 CYP4F2 (0.68) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL1661139 0.92 CYP4F2 (0.65) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17756702 0.91 CYP4F2 (0.60) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL20597884 0.91 CYP4F2 (0.59) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL6257314 0.90 CYP4F2 (0.85) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL6254544 0.90 CYP4F2 (0.85) CYP4F2CYP4A11HTTPKMTHRB
SCHEMBL17762731 0.90 CYP4F2 (0.58) CYP4F2CYP4A11HTTPKMTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164845-A Preparation method of beipezite 山东铂源药业股份有限公司 2024-06-11 CN claimed
CN-117924067-A Method for preparing bevacizidine by utilizing microchannel reactor 山东铂源药业股份有限公司 2024-04-26 CN claimed
CN-117623923-A Synthesis method of bevacizidine acid intermediate compound 安徽艾立德制药有限公司 2024-03-01 CN claimed
WO-2023187833-A1 A NOVEL SALT OF BEMPEDOIC ACID ENALTEC LABS PRIVATE LIMITED (IN) 2023-10-05 WO claimed
CN-116410086-A Method for preparing isobutyric acid derivative 苏州特瑞药业股份有限公司 2023-07-11 CN claimed
CN-111675614-B Method for synthesizing 7-bromo-2,2-dimethylheptanoic acid ethyl ester 爱斯特(成都)生物制药股份有限公司 2022-11-29 CN claimed
CN-112047840-A Synthesis method of 7-bromo-2, 2-dimethylheptanoic acid ethyl ester and product obtained by synthesis 山东药品食品职业学院 2020-12-08 CN claimed
CN-111675614-A Method for synthesizing 7-bromo-2, 2-dimethylheptanoic acid ethyl ester 爱斯特(成都)生物制药股份有限公司 2020-09-18 CN claimed
CN-122010712-A Synthesis method of bevacizidine and intermediate thereof 扬州奥锐特药业有限公司 2026-05-12 CN disclosed
EP-4695266-A1 SUBSTITUTED ALKANOIC-DIACIDS COMPOUND AND COMPOSITION AND USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
CN-121318692-A One-pot preparation method of beipezite intermediate 天科(荆州)制药有限公司 2026-01-13 CN disclosed
WO-2025092475-A1 SYNTHESIS METHOD FOR BEMPEDOIC ACID AND BEMPEDOIC ACID INTERMEDIATE, AND BEMPEDOIC ACID INTERMEDIATE 扬州奥锐特药业有限公司 2025-05-08 WO disclosed
CN-119930422-A Preparation method of bevacizidine acid and intermediate thereof 扬州奥锐特药业有限公司 2025-05-06 CN disclosed
WO-2024213143-A1 SUBSTITUTED ALKANOIC-DIACIDS COMPOUND AND COMPOSITION AND USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
EP-0320501-A2 Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1989-06-14 EP disclosed
EP-0304271-A2 Omega-arylsulphonamidoalkanoic acids for treatment of thromboxane medited diseases SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-02-22 EP disclosed
US-4798838-A ANTICOAGULANTS, ANTICHOLESTEROL AGENTS YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1989-01-17 US disclosed
US-4795753-A Certain pyridyl or imidazol-1-yl-alkyleneoxy-(or amino)phenoxy-alkanoates having lipid lowering activity YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1989-01-03 US disclosed
US-4794113-A ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-12-27 US disclosed
EP-0130077-A2 Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1985-01-02 EP disclosed