SCHEMBL186838

SCHEMBL186838

CCOC(=O)C(C)(C)CCCCBr

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.68
CYP4A11 Q02928 3/20 0.68
PKM P14618 3/20 0.44
THRB P10828 1/20 0.44
HTT P42858 1/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.39
MMP8 P22894 1/20 0.35
CYP1A2 P05177 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ELANE P08246 2/20 0.33
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ABCB11 O95342 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9871166 0.98 CYP4F2 (0.71) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL186284 0.98 CYP4F2 (0.71) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL2142612 0.98 CYP4F2 (0.71) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL186818 0.98 CYP4F2 (0.71) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL1661139 0.94 CYP4F2 (0.65) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL17756702 0.93 CYP4F2 (0.60) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL17762731 0.92 CYP4F2 (0.58) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL20597884 0.89 CYP4F2 (0.59) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL6257314 0.88 CYP4F2 (0.85) CYP4F2CYP4A11PKMTHRBHTT
SCHEMBL6254544 0.88 CYP4F2 (0.85) CYP4F2CYP4A11PKMTHRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410086-A Method for preparing isobutyric acid derivative 苏州特瑞药业股份有限公司 2023-07-11 CN claimed
US-20220081385-A1 NOVEL SALTS AND POLYMORPHIC FORM OF BEMPEDOIC ACID LUPIN LIMITED (IN) 2022-03-17 US claimed
EP-3906231-A2 NOVEL SALTS AND POLYMORPHIC FORM OF BEMPEDOIC ACID Lupin Limited (IN) 2021-11-10 EP claimed
CN-113227061-A Novel salts and polymorphs of bipedac acid 印度鲁宾有限公司 2021-08-06 CN claimed
WO-2020141419-A2 NOVEL SALTS AND POLYMORPHIC FORM OF BEMPEDOIC ACID LUPIN LIMITED (IN) 2020-07-09 WO claimed
EP-4281058-B1 FUNCTIONALIZED LONG-CHAIN DICARBOXYLIC ACIDS, AND THEIR USE FOR TREATMENT OF KIDNEY DISEASES ESPERVITA THERAPEUTICS INC (US) 2026-03-18 EP disclosed
EP-4695266-A1 SUBSTITUTED ALKANOIC-DIACIDS COMPOUND AND COMPOSITION AND USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
US-12396972-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2025-08-26 US disclosed
US-20240417383-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF THE SALK INSTITUTE FOR BIOLOGICAL STUDIES 2024-12-19 US disclosed
US-20240398737-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE ESPERVITA THERAPEUTICS, INC. 2024-12-05 US disclosed
WO-2024213143-A1 SUBSTITUTED ALKANOIC-DIACIDS COMPOUND AND COMPOSITION AND USE THEREOF META PHARMACEUTICALS (HK) LIMITED (CN) 2024-10-17 WO disclosed
CN-113024467-B PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof 米托布里奇公司 2024-08-06 CN disclosed
US-4794113-A ANTICHOLESTEROL, ANTILIPEMIC, ANTICOAGULANT YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1988-12-27 US disclosed
US-4758573-A Heterocyclic group-containing compounds G. D. SEARLE & CO. (US) 1988-07-19 US disclosed
EP-0260613-A2 Imidazopyridine derivatives, their preparation and their use as PAF-antagonists G.D. Searle & Co. (US) 1988-03-23 EP disclosed
EP-0254590-A2 Aryl-di(thio)ether derivatives as antitumoral pharmaceutical compounds YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1988-01-27 EP disclosed
EP-0105575-B1 1-(1H-IMIDAZOLYL), 1-N-MORPHOLINYL AND PYRIDYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM G.D. Searle & Co. (US) 1987-03-04 EP disclosed
US-4579862-A TREATMENT OF CEREBROVASCULAR DISEACE, ISCHEMIA, DIABETES, ANGINA, MYOCARDIAL INFARCTION G. D. SEARLE & CO. (US) 1986-04-01 US disclosed
EP-0130077-A2 Phenoxy derivatives, their preparation, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1985-01-02 EP disclosed
EP-0105575-A1 1-(1H-imidazolyl), 1-N-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them G.D. Searle & Co. (US) 1984-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12396972-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR CYP4F2 847/4885CYP4A11 552/4885PKM 1257/4885
US-20220081385-A1 NOVEL SALTS AND POLYMORPHIC FORM OF BEMPEDOIC ACID HADH, ALDH5A1, ACAD9 CYP4F2 184/4885CYP4A11 197/4885PKM 2411/4885
US-20240398737-A1 FUNCTIONALIZED LONG-CHAIN HYDROCARBON MONO- AND DI-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF, AND THEIR USE FOR THE PREVENTION OR TREATMENT OF DISEASE AHR, PKD1, CFTR CYP4F2 847/4885CYP4A11 552/4885PKM 1257/4885
US-20240417383-A1 PPAR AGONISTS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF PPARG, PPARD, PPARA CYP4F2 2116/4885CYP4A11 735/4885PKM 452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.