Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18682250 | 1.00 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL18682244 | 0.97 | THRA (0.56) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL18682245 | 0.96 | THRA (0.54) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL14926459 | 0.90 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL15927334 | 0.90 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL14926454 | 0.90 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL15762952 | 0.90 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL14926447 | 0.90 | THRA (0.59) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL14926445 | 0.89 | THRA (0.57) | THRATHRBESR1NPC1MAPT | |
| SCHEMBL14926441 | 0.88 | THRA (0.59) | THRATHRBESR1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088777-A1 | LIQUID CRYSTAL ALIGNMENT LAYER | DIC CORPORATION (JP) | 2017-03-30 | — | — | US | disclosed |