Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 12/20 | 0.40 |
| ▸ | KLK1 | P06870 | 5/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1868236 | 1.00 | MASP2 (0.42) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1867143 | 0.92 | MASP2 (0.43) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1867146 | 0.92 | MASP2 (0.43) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1873305 | 0.91 | MASP2 (0.42) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1873309 | 0.91 | MASP2 (0.42) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1867199 | 0.89 | MASP2 (0.43) | MASP2KLKB1KLK1FLT3 | |
| SCHEMBL1867203 | 0.89 | MASP2 (0.43) | MASP2KLKB1KLK1FLT3 | |
| SCHEMBL1866499 | 0.89 | MASP2 (0.43) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1866502 | 0.89 | MASP2 (0.43) | MASP2KLKB1KLK1ABL1FLT3 | |
| SCHEMBL1871675 | 0.88 | MASP2 (0.42) | MASP2KLKB1KLK1ABL1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051672-A1 | AZAINDOLE DERIVATIVES | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |