SCHEMBL18683148

SCHEMBL18683148

CC(N)[C@H]1OC[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17509637 0.95 THRB (0.35) THRBLMNA
SCHEMBL4871281 0.83 THRB (0.32) THRBLMNA
SCHEMBL9914081 0.81 THRB (0.38) THRBLMNA
SCHEMBL11946930 0.81 THRB (0.38) THRBLMNA
SCHEMBL11954391 0.81 THRB (0.38) THRBLMNA
SCHEMBL24988552 0.81 THRB (0.38) THRBLMNA
SCHEMBL14025402 0.81 THRB (0.38) THRBLMNA
SCHEMBL16491129 0.81 THRB (0.38) THRBLMNA
SCHEMBL12311769 0.81 THRB (0.38) THRBLMNA
SCHEMBL14556001 0.81 THRB (0.38) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017049386-A1 SUPPRESSORS OF PREMATURE TERMINATION CODONS AS THERAPEUTICS AND METHODS FOR THEIR USE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2017-03-30 WO disclosed