SCHEMBL1868334

SCHEMBL1868334

CCCCCCCCCCCC1(O)CC1

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.49
OPRD1 P41143 2/20 0.49
OPRK1 P41145 2/20 0.49
OPRL1 P41146 2/20 0.49
TSHR P16473 2/20 0.42
THRB P10828 1/20 0.42
LMNA P02545 2/20 0.39
ALDH1A1 P00352 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17607279 1.00 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL17730835 1.00 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL17731291 1.00 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL17607210 1.00 OPRM1 (0.49) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL4437885 0.97
SCHEMBL28957502 0.90 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL7163027 0.90 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL10442021 0.90 OPRM1 (0.46) OPRM1OPRD1OPRK1OPRL1TSHR
SCHEMBL5169885 0.89
SCHEMBL25227088 0.88 OPRM1 (0.45) OPRM1OPRD1OPRK1OPRL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109846733-A A kind of root of Dahurain angelica mildy wash and its preparation process 陈善堂生物制药有限责任公司 2019-06-07 CN claimed
WO-2017061971-A1 TOPICAL MINOXIDIL COMPOSITION ASSOS ILAÇ KIMYA GIDA ÜRÜNLERI ÜRETIM VE TIC. A. Ş. (TR) 2017-04-13 WO claimed
EP-3875097-B1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF NEXTPHASE THERAPEUTICS INC (US) 2023-06-07 EP disclosed
EP-3875097-A1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF Mariñas Pardo, Luis (ES) 2021-09-08 EP disclosed
US-20210244767-A1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF NextPhase Therapeutics, Inc. 2021-08-12 US disclosed
US-20210236560-A1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF NextPhase Therapeutics, Inc. 2021-08-05 US disclosed
EP-3806872-A1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF Mariñas Pardo, Luis (ES) 2021-04-21 EP disclosed
EP-3359198-B1 TOPICAL MINOXIDIL COMPOSITION ASSOS ILAC KIMYA GIDA UERUENLERI UERETIM VE TIC A S (TR) 2020-05-13 EP disclosed
WO-2019238952-A1 PHARMACEUTICAL COMPOSITION FOR DERMATOLOGY AND USES THEREOF MARINAS PARDO LUIS (ES) 2019-12-19 WO disclosed
US-20190083492-A1 TOPICAL MINOXIDIL COMPOSITION ASSOS ILAÇ KIMYA GIDA ÜRÜNLERI ÜRETIM VE TIC. A. ? . (TR) 2019-03-21 US disclosed
CN-108929803-A Strong dirt-removing house detergent 常州市新晞电气制造有限公司 2018-12-04 CN disclosed
CN-108728268-A Less toxic house detergent 柏建华 2018-11-02 CN disclosed
WO-2017061971-A1 TOPICAL MINOXIDIL COMPOSITION ASSOS ILAÇ KIMYA GIDA ÜRÜNLERI ÜRETIM VE TIC. A. Ş. (TR) 2017-04-13 WO disclosed
EP-2493462-A1 PTEROSTILBENE (PTER) FOR USE IN THE PREVENTION AND/OR TREATMENT OF SKIN DISEASES, DAMAGES OR INJURES Green Molecular, S.L. (ES) 2012-09-05 EP disclosed
EP-2488548-A1 A LOW DENSITY LIPOPROTEIN-RELATED PROTEIN 1 SPLICE VARIANT AS CANCER MARKER Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung (DE) 2012-08-22 EP disclosed
WO-2011054644-A1 A LOW DENSITY LIPOPROTEIN-RELATED PROTEIN 1 SPLICE VARIANT AS CANCER MARKER Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2011-05-12 WO disclosed
WO-2011051483-A1 PTEROSTILBENE (PTER) FOR USE IN THE PREVENTION AND/OR TREATMENT OF SKIN DISEASES, DAMAGES OR INJURES GREEN MOLECULAR, S.L (ES) 2011-05-05 WO disclosed
WO-2001089488-A1 PLASTER CONTAINING ESTROGEN, WITH AN ACTIVE AGENT RESERVOIR BASED ON ETHYLCELLULOSE, POLYOXYETHYLENE LAURYL ALCOHOL AND AN ETHYLENE-VINYLACETATE-VINYLPYRROLIDONE COPOLYMER LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2001-11-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190083492-A1 TOPICAL MINOXIDIL COMPOSITION MCOLN3, ACADVL, MCOLN1 OPRM1 1342/4885OPRD1 675/4885OPRK1 2072/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.