SCHEMBL186839

SCHEMBL186839

CCCCOC(=O)C(C(OCc1ccc2c(c1)OCO2)=[N+](S(=O)(=O)C(F)(F)F)S(=O)(=O)C(F)(F)F)c1[nH]cc[n+]1C

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
TSHR P16473 5/20 0.34
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
HTT P42858 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
LMNA P02545 2/20 0.34
ALDH1A1 P00352 4/20 0.33
PKM P14618 2/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
NAAA Q02083 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL188022 0.85 CYP3A4 (0.47) CYP3A4TSHRMEN1KMT2AHTT
SCHEMBL786777 0.81 CYP3A4 (0.41) CYP3A4TSHRMEN1KMT2AHTT
SCHEMBL786416 0.79 CYP3A4 (0.39) CYP3A4TSHRMEN1KMT2AHTT
SCHEMBL785307 0.77 CYP3A4 (0.38) CYP3A4TSHRMEN1KMT2AHTT
Hydrochloric Acid SCHEMBL187311 0.74 CYP3A4 (0.51) CYP3A4HTTSMN1; SMN2LMNAALDH1A1
SCHEMBL786373 0.69 CYP3A4 (0.53) CYP3A4TSHRMEN1KMT2AHTT
Bromide SCHEMBL785308 0.68 CYP3A4 (0.52) CYP3A4TSHRMEN1KMT2AHTT
SCHEMBL785950 0.66 CYP3A4 (0.47) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL786171 0.65 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2
SCHEMBL786172 0.65 CYP3A4 (0.48) CYP3A4TSHRMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2401258-A1 IONIC LIQUID SOLVENTS Dublin City University (IE) 2012-01-04 EP claimed
WO-2010097412-A1 IONIC LIQUID SOLVENTS DUBLIN CITY UNIVERSITY (IE) 2010-09-02 WO claimed