SCHEMBL18686111

SCHEMBL18686111

Cc1cc(Br)c(P(c2ccccc2)c2ccccc2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
DRD1 P21728 2/20 0.39
ALDH1A1 P00352 1/20 0.38
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
TSHR P16473 2/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
NQO2 P16083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30138990 1.00 CYP3A4 (0.42) CYP3A4TDP1DRD1ALDH1A1ESR1
SCHEMBL14603699 0.98 CYP3A4 (0.41) CYP3A4TDP1DRD1ALDH1A1ESR1
SCHEMBL30138939 0.83 CYP3A4 (0.50) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL1241093 0.82 CYP3A4 (0.41) CYP3A4TDP1DRD1ALDH1A1ESR1
SCHEMBL29141883 0.78 TDP1 (0.41) CYP3A4TDP1DRD1ALDH1A1ESR1
SCHEMBL12889878 0.77 CYP3A4 (0.48) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL28906236 0.76 CYP3A4 (0.42) CYP3A4TDP1DRD1ESR1ESR2
SCHEMBL28902398 0.76 LCK (0.41) CYP3A4TDP1DRD1ALDH1A1KMT2A
SCHEMBL17227511 0.73 TDP1 (0.39) CYP3A4TDP1DRD1ALDH1A1ESR1
SCHEMBL12446368 0.72 CYP3A4 (0.42) CYP3A4TDP1DRD1ALDH1A1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115433227-A Multidentate phosphine coordinated copper trihalo tri-type complex, and synthesis method and application thereof 黑龙江大学 2022-12-06 CN disclosed
CN-115433213-A Aromatic phosphine copper complex, and synthesis method and application thereof 黑龙江大学 2022-12-06 CN disclosed
EP-3150613-A1 P-CHIROGENIC ORGANOPHOSPHORUS COMPOUNDS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-04-05 EP disclosed