Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12889878 | 0.84 | CYP3A4 (0.48) | CYP3A4TDP1ESR1ESR2TSHR | |
| SCHEMBL18686111 | 0.82 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL30138990 | 0.82 | CYP3A4 (0.42) | CYP3A4TDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL14603699 | 0.81 | CYP3A4 (0.41) | CYP3A4TDP1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL15710239 | 0.73 | ALDH1A1 (0.46) | CYP3A4TDP1ALDH1A1ESR1ESR2 | |
| SCHEMBL15710240 | 0.73 | ALDH1A1 (0.46) | CYP3A4TDP1ALDH1A1ESR1ESR2 | |
| SCHEMBL30138939 | 0.73 | CYP3A4 (0.50) | CYP3A4TDP1CYP1A2ESR1ESR2 | |
| SCHEMBL10796893 | 0.72 | TDP1 (0.44) | CYP3A4TDP1ALDH1A1ESR1ESR2 | |
| SCHEMBL9165318 | 0.72 | TDP1 (0.44) | CYP3A4TDP1ALDH1A1CYP1A2ESR1 | |
| SCHEMBL29535212 | 0.70 | CYP3A4 (0.52) | CYP3A4TDP1ALDH1A1CYP1A2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660608-B1 | OLIGOMER AND POLYMER COMPRISING TRIPHENYL PHOSPHINE UNITS | MERCK PATENT GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| EP-1660608-B1 | OLIGOMER AND POLYMER COMPRISING TRIPHENYL PHOSPHINE UNITS | MERCK PATENT GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| US-7893172-B2 | Oligomer and polymer comprising triphenyl phosphine units | MERCK PATENT GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-7893172-B2 | Oligomer and polymer comprising triphenyl phosphine units | MERCK PATENT GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-7893172-B2 | Oligomer and polymer comprising triphenyl phosphine units | MERCK PATENT GMBH (DE) | 2011-02-22 | — | — | US | disclosed |
| US-20070031698-A1 | Oligomer and polymer comprising triphenyl phosphine units | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-02-08 | — | — | US | disclosed |
| US-20070031698-A1 | Oligomer and polymer comprising triphenyl phosphine units | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-02-08 | — | — | US | disclosed |
| US-20070031698-A1 | Oligomer and polymer comprising triphenyl phosphine units | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2007-02-08 | — | — | US | disclosed |
| EP-1660608-A1 | OLIGOMER AND POLYMER COMPRISING TRIPHENYL PHOSPHINE UNITS | Covion Organic Semiconductors GmbH (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005017065-A1 | OLIGOMER AND POLYMER COMPRISING TRIPHENYL PHOSPHINE UNITS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-02-24 | — | — | WO | disclosed |