Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 20/20 | 1.00 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.52 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18686555 | 1.00 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL19091946 | 0.91 | CACNA1H (0.83) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686590 | 0.91 | CACNA1H (0.83) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686592 | 0.91 | CACNA1H (0.83) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686551 | 0.90 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686553 | 0.90 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL26082237 | 0.86 | CACNA1H (0.75) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686523 | 0.85 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL18686521 | 0.85 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I | |
| SCHEMBL19091655 | 0.85 | CACNA1H (1.00) | CACNA1HCACNA1GCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150598-B1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD (JP) | 2019-02-13 | — | — | EP | disclosed |
| US-9856250-B2 | Substituted tropane derivatives | TOA EIYO LTD. (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA EIYO LTD. (JP) | 2017-07-06 | — | — | US | disclosed |
| EP-3150598-A1 | SUBSTITUTED TROPANE DERIVATIVES | TOA Eiyo Ltd. (JP) | 2017-04-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190699-A1 | SUBSTITUTED TROPANE DERIVATIVES | CACNA1G, CACNA1H, CACNA1I | CACNA1H 2/4885CACNA1G 1/4885CACNA1I 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.