Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250089 | 0.99 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL249995 | 0.93 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL19492113 | 0.90 | TGFBR1 (0.82) | TGFBR1MAPK14 | |
| SCHEMBL248618 | 0.89 | TGFBR1 (0.82) | TGFBR1MAPK14 | |
| SCHEMBL249867 | 0.87 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL249473 | 0.86 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL247976 | 0.86 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL29631969 | 0.86 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL250006 | 0.85 | TGFBR1 (1.00) | TGFBR1MAPK14 | |
| SCHEMBL19492220 | 0.84 | TGFBR1 (0.78) | TGFBR1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588479-B3 | 2-PYRIDYL SUBSTITUTED IMIDAZOLES AS THERAPEUTIC ALK5 AND/OR ALK4 INHIBITORS | EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUND (KR) | 2017-03-29 | — | — | EP | disclosed |