Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.69 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.66 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.65 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7480761 | 0.85 | FGFR2 (0.78) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL7481076 | 0.85 | EGFR (0.78) | EGFRFGFR2PDGFRAPDGFRB | |
| SCHEMBL31061546 | 0.83 | EGFR (0.74) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL19373176 | 0.83 | EGFR (0.74) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL26254832 | 0.83 | FGFR2 (0.62) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL31060325 | 0.82 | FGFR2 (0.78) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL17117826 | 0.82 | FGFR2 (0.78) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL18688394 | 0.82 | EGFR (0.61) | EGFRFGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL21769423 | 0.82 | FGFR2 (0.57) | FGFR2PDGFRAPDGFRBKDR | |
| SCHEMBL7490337 | 0.82 | EGFR (0.72) | EGFRFGFR2PDGFRAPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049462-A1 | NOVEL FLT3 KINASE INHIBITOR AND USES THEREOF | 合肥中科普瑞昇生物医药科技有限公司 | 2017-03-30 | — | — | WO | disclosed |