Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18420561 | 0.94 | NPC1 (0.32) | MAPTCA12CA1CA9 | |
| Hydrochloric Acid SCHEMBL18689958 | 0.93 | POLB (0.33) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL18420191 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL5079597 | 0.93 | NPC1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL18689962 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL18420297 | 0.92 | CA9 (0.31) | MEN1KMT2AMAPTCA12CA1 | |
| Hydrochloric Acid SCHEMBL1643823 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL18689967 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL18689974 | 0.88 | NPC1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL18689949 | 0.88 | PLK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9771448-B2 | Olefin-based resin, method for producing same and propylene-based resin composition | MITSUI CHEMICALS, INC. (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20170096514-A1 | OLEFIN-BASED RESIN, METHOD FOR PRODUCING SAME AND PROPYLENE-BASED RESIN COMPOSITION | MITSUI CHEMICALS, INC. (JP) | 2017-04-06 | — | — | US | disclosed |