Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9956855 | 0.74 | CYP2D6 (0.53) | EPHX1TDP1NPC1RAB9ACA12 | |
| Hydrochloric Acid SCHEMBL21640704 | 0.72 | EPHX1 (0.49) | EPHX1TDP1NPC1RAB9ARORC | |
| SCHEMBL13284765 | 0.72 | PRCP (0.49) | EPHX1MEN1KMT2A | |
| SCHEMBL1870892 | 0.72 | HPGD (0.34) | HPGDUSP2SMN1; SMN2 | |
| SCHEMBL18028783 | 0.72 | TDP1 (0.72) | EPHX1TDP1NPC1RAB9ACA12 | |
| SCHEMBL3394009 | 0.72 | NPC1 (0.43) | EPHX1TDP1NPC1RAB9ANAMPT | |
| SCHEMBL18936070 | 0.72 | TDP1 (0.43) | EPHX1TDP1NPC1RAB9ACA12 | |
| SCHEMBL1438739 | 0.71 | EPHX1 (0.51) | EPHX1NPC1RAB9ASMN1; SMN2RORC | |
| SCHEMBL2930782 | 0.71 | NAMPT (0.42) | EPHX1TDP1NPC1RAB9AHPGD | |
| SCHEMBL13393118 | 0.70 | EPHX1 (0.50) | EPHX1TDP1RORCNAMPTPDE8B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051961-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2011-05-05 | — | — | WO | claimed |