Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360130 | 0.84 | KCNH3 (0.37) | KCNH3ALDH1A1KDM1A | |
| SCHEMBL4396896 | 0.84 | HPGD (0.33) | HPGDUSP2SMN1; SMN2 | |
| SCHEMBL1869455 | 0.72 | EPHX1 (0.44) | HPGDUSP2SMN1; SMN2 | |
| SCHEMBL4572204 | 0.71 | SAT1 (0.48) | KCNH3 | |
| SCHEMBL28707592 | 0.71 | NPC1 (0.34) | HPGDKCNH3 | |
| SCHEMBL6929311 | 0.70 | DRD4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL4669450 | 0.70 | SAT1 (0.47) | KCNH3 | |
| SCHEMBL17376511 | 0.68 | HPGD (0.54) | HPGDALDH1A1USP2SMN1; SMN2 | |
| SCHEMBL4962562 | 0.68 | SAT1 (0.45) | HPGDKCNH3 | |
| SCHEMBL21744423 | 0.67 | MAPT (0.38) | KCNH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483266-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | Cadila Healthcare Limited (IN) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011051961-A1 | COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES | CADILA HEALTHCARE LIMITED (IN) | 2011-05-05 | — | — | WO | disclosed |