Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15426103 | 0.95 | KDM7A (0.55) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL15426049 | 0.91 | KDM7A (0.55) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL15426069 | 0.89 | KDM7A (0.53) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL15426048 | 0.89 | KDM7A (0.53) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL14649657 | 0.88 | KDM7A (0.55) | KDM7AHTTMAPK1TDP1L3MBTL1 | |
| SCHEMBL14707711 | 0.87 | KDM5A (0.63) | KDM7AESR1PGRCHRM2HTR1A | |
| SCHEMBL15426077 | 0.86 | KDM7A (0.51) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL15426085 | 0.83 | KDM7A (0.53) | KDM7AHTTPTGS2MAPK1TDP1 | |
| SCHEMBL14552008 | 0.83 | HTT (0.62) | HTTPTGS2MAPK1TDP1L3MBTL1 | |
| SCHEMBL14649659 | 0.82 | ESR1 (0.70) | LMNAESR1PGRCHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611242-B2 | Process for preparation of dronedarone by N-butylation | SANOFI (FR) | 2017-04-04 | — | — | US | disclosed |