Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18696169 | 0.95 | KDM7A (0.57) | KDM7ARXFP1HTTMAPK1TDP1 | |
| SCHEMBL15426085 | 0.88 | KDM7A (0.53) | KDM7ARXFP1HTTMAPK1TDP1 | |
| SCHEMBL15426049 | 0.88 | KDM7A (0.55) | KDM7AHTTMAPK1TDP1L3MBTL1 | |
| SCHEMBL15426077 | 0.86 | KDM7A (0.51) | KDM7AHTTMAPK1TDP1L3MBTL1 | |
| SCHEMBL15426069 | 0.86 | KDM7A (0.53) | KDM7ARXFP1HTTMAPK1TDP1 | |
| SCHEMBL15426048 | 0.86 | KDM7A (0.53) | KDM7AHTTMAPK1TDP1L3MBTL1 | |
| SCHEMBL16687345 | 0.84 | HTT (0.68) | KDM7ARXFP1HTTMAPK1TDP1 | |
| SCHEMBL14649657 | 0.83 | KDM7A (0.55) | KDM7AHTTMAPK1TDP1L3MBTL1 | |
| SCHEMBL14552008 | 0.83 | HTT (0.62) | HTTMAPK1TDP1L3MBTL1PTGS2 | |
| SCHEMBL14707711 | 0.82 | KDM5A (0.63) | KDM7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9024046-B2 | Reductive amination process for preparation of dronedarone using amine intermediary compound | SANOFI (FR) | 2015-05-05 | — | — | US | disclosed |
| US-20140018554-A1 | REDUCTIVE AMINATION PROCESS FOR PREPARATION OF DRONEDARONE USING AMINE INTERMEDIARY COMPOUND | SANOFI (FR) | 2014-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140018554-A1 | REDUCTIVE AMINATION PROCESS FOR PREPARATION OF DRONEDARONE USING AMINE INTERMEDIARY COMPOUND | CYP2D6, CYP2B6, CYP11B2 | KDM7A 1343/4885RXFP1 3778/4885HTT 913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.