Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.42 |
| ▸ | PRKDC | P78527 | 7/20 | 0.41 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18933422 | 0.97 | ALOX5 (0.57) | ALOX5GGPS1PLA2G2APLA2G4APRKDC | |
| SCHEMBL18697103 | 0.94 | ALOX5 (0.55) | ALOX5GGPS1PRKDCPTGES2MMP12 | |
| SCHEMBL19743191 | 0.93 | ALOX5 (0.56) | ALOX5GGPS1PRKDCPTGES2MEN1 | |
| SCHEMBL26564252 | 0.92 | ALOX5 (0.51) | ALOX5GGPS1PRKDCPTGES2MMP12 | |
| SCHEMBL22181939 | 0.87 | ALOX5 (0.63) | ALOX5GGPS1PLA2G2APLA2G4APRKDC | |
| SCHEMBL10442976 | 0.87 | ALOX5 (0.49) | ALOX5GGPS1PLA2G2APLA2G4APRKDC | |
| SCHEMBL18933533 | 0.86 | ALOX5 (0.50) | ALOX5GGPS1PRKDCPTGES2MEN1 | |
| SCHEMBL9917136 | 0.85 | ALOX5 (0.57) | ALOX5GGPS1PLA2G2APLA2G4APRKDC | |
| SCHEMBL17057166 | 0.84 | ALOX5 (0.64) | ALOX5GGPS1PLA2G2APLA2G4APRKDC | |
| SCHEMBL25140460 | 0.83 | ALOX5 (0.58) | ALOX5GGPS1PLA2G2APLA2G4APRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9614160-B2 | Aromatic amine derivatives and organic electroluminescent elements using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-04-04 | — | — | US | disclosed |