Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.60 |
| ▸ | MAP4K1 | Q92918 | 7/20 | 0.60 |
| ▸ | KLK1 | P06870 | 11/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20616378 | 0.88 | KLKB1 (0.55) | KLKB1MAP4K1KLK1 | |
| SCHEMBL19354570 | 0.84 | KLKB1 (0.45) | KLKB1MAP4K1KLK1 | |
| SCHEMBL21657068 | 0.81 | KLKB1 (0.59) | KLKB1MAP4K1KLK1 | |
| SCHEMBL18458794 | 0.81 | KLKB1 (0.55) | KLKB1MAP4K1KLK1 | |
| SCHEMBL19354844 | 0.80 | KLKB1 (0.57) | KLKB1MAP4K1KLK1 | |
| SCHEMBL17442507 | 0.75 | KLKB1 (1.00) | KLKB1MAP4K1KLK1 | |
| SCHEMBL20282926 | 0.74 | KLKB1 (0.57) | KLKB1MAP4K1KLK1 | |
| SCHEMBL18697145 | 0.74 | KLKB1 (0.57) | KLKB1MAP4K1 | |
| SCHEMBL20616377 | 0.71 | KLKB1 (0.57) | KLKB1MAP4K1 | |
| SCHEMBL21657106 | 0.70 | KLKB1 (0.46) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611252-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2017-04-04 | — | — | US | disclosed |