SCHEMBL18697226

SCHEMBL18697226

Cc1ccc(N2C(=O)OC3(CC(C)(C)N(O)C(C)(C)C3)C2=O)cc1N1C(=O)NC2(CC(C)(C)N(O)C(C)(C)C2)C1=O

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
ALOX15 P16050 1/20 0.32
AR P10275 1/20 0.31
LMNA P02545 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124685 0.83 POLB (0.33) POLBARLMNA
SCHEMBL10124688 0.82 MAPT (0.30) MAPT
SCHEMBL11479457 0.77 POLB (0.43) POLBALDH1A1MAPTALOX15AR
SCHEMBL10124699 0.71 POLB (0.31) POLB
SCHEMBL10124662 0.70 POLB (0.36) POLBALDH1A1MAPTALOX15AR
SCHEMBL11479153 0.68 ELANE (0.43) POLBALDH1A1MAPTLMNA
SCHEMBL10124669 0.67 POLB (0.34) POLBALDH1A1MAPTALOX15AR
SCHEMBL11477808 0.62 KMT2A (0.48) ALDH1A1MAPT
SCHEMBL11478197 0.62 POLB (0.53) POLBMAPTAR
SCHEMBL10124675 0.59 ELANE (0.36) ALDH1A1ARLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed