SCHEMBL10124675

SCHEMBL10124675

CON1C(C)(C)CC2(CC1(C)C)OC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
HSD11B1 P28845 2/20 0.35
ALDH1A1 P00352 3/20 0.35
PGR P06401 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAOA P21397 1/20 0.34
AR P10275 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
CTSG P08311 1/20 0.32
PRTN3 P24158 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18697264 0.87 ELANE (0.35) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL10124677 0.86 ELANE (0.39) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL10124680 0.84 ELANE (0.38) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL10124678 0.83 CACNA1B (0.35) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL10124682 0.80 ELANE (0.38) ELANEALDH1A1CYP2C9CYP2C19MEN1
SCHEMBL10124681 0.80 ELANE (0.38) ELANEALDH1A1CYP2C9CYP2C19MEN1
SCHEMBL10124693 0.79 ALDH1A1 (0.39) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL11376669 0.76 ELANE (0.42) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL10124651 0.75 POLB (0.42) ELANECACNA1BAPBA1HSD11B1ALDH1A1
SCHEMBL13050166 0.74 TRIP13 (0.38) ALDH1A1ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885CACNA1B 4469/4885APBA1 3485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.