Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12726885 | 0.92 | TLR7 (0.60) | TLR7 | |
| SCHEMBL12726899 | 0.92 | TLR7 (0.61) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726893 | 0.90 | TLR7 (0.65) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL2058848 | 0.90 | TLR7 (0.60) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL15695425 | 0.90 | TLR7 (0.62) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12726948 | 0.89 | TLR7 (0.57) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12305185 | 0.89 | TLR7 (0.59) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL2058885 | 0.89 | TLR7 (0.61) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL12305180 | 0.89 | TLR7 (0.61) | TLR7CYP3A4CYP2D6 | |
| SCHEMBL15692285 | 0.88 | TLR7 (0.56) | TLR7CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9611268-B2 | Modulators of toll-like receptor 7 | GILEAD SCIENCES, INC. (US) | 2017-04-04 | — | — | US | disclosed |